We have a Dodge Ram 1500 Quad Cab with four Yakima Bedheads. Gas mileage isn't great but the truck doesn't have many miles. Last one my husband had (totalled it) was getting 22 mpg highway once it hit 50k. Right now we get about 18 mpg highway, except when we went to New Mexico and got 22 mpg the whole 2,000 mile trip with 4 bikes in the bed. One bike fits behind the seat nicely so I can bring mine to work. I am a big fan of our truck.