Move the mouse to the left of the keyboard. This works better ergonomically if you do not have a number pad on the left of the keyboard. you can buy keyboards that lack the number pad, or get a plug in number pad to position elsewhere than left of the keyboard ( i have a goldstar keyboard that I like a lot)
I am a rightie but started mousing on the left further to a sprained thumb about ten years ago and never went back. as a small bonus, I can mouse with one hand and take notes w/ my right hand
further to the adaptation conversation above, after my hand injury, i became very adept at doing things with the fingertips of my right middle, ring and pinkie fingers which protruded about 1/2 inch from my cast. After my cast was removed, I could not use my thumb for about 6 months and became adept at using my index and middle finger to do things where I formerly used my thumb and index finger. I still find myself holding things between the index and middle finger sometimes



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