I decided a long time ago that unless I was happy, no one would be happy. Having a supportive partner and kids helped...
People used to think I was super woman, but really, I did things that others wouldn't have, especially when my kids were young. I got up at 4:30 AM to exercise, so it didn't interfere with other stuff. I taught my kids to help with housework at an early age and that worked until I could afford a house cleaner. But most of all, I didn't expect that I would do everything in the house; my DH has always done more than his share and i think that eliminated a lot of the stress.
Lately, I have rid myself of negative people. That included some family, but really, I am happier without them. If certain activities or people are a drain on your time, then I would look carefully at ow much you need to continue with them. I would rather be riding than spending time with my negative friend or aunt. It sounds a little cruel, but you have to decide what is best for you, once the basic needs are met. It's liberating...