Yes, I find my folder (18" wheels) more maneuverable than my road bike (700c).
I don't notice on most roads, but I will notice a bit on technical (very tight twisty) descents.
I would notice more if I were doing something like riding around a bike barrier in a pedestrian underpass or overpass. (ahem)
ETA: It is not just the wheel diameter, it is also affected a lot by the bike geometry and to a lesser extent the tire width.



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