I've worn the injiji toe socks for several marathons (and bike and run for Ironman), my biggest complaint is how they wear (faster than other socks, and not cushioned or anything). I do still get blisters, but they aren't like those - they take longer to form and aren't so blistery, though that could be because my feet are so calloused Blisters also don't form under my toes or between my toes, which are problems I had before wearing them. What I get now is rubbing on the side of my big toe/foot because of how my shoes wear.

I do have fewer blister problems and discomfort running in triathlons than running by itself (as long as I wear the injijis - if I don't, I get blisters under/between toes after 5-10k). Go figure.