Is your saddle level? If not, you could be putting too much pressure on one area. Even the best saddle takes a certain break in time. I'd image that with a new bike, you're riding it more often than before, so your body needs to adjust to that position on the saddle.

Certainly the shorts are worth looking at. I've learned that big thick chamois doesn't equal a comfy, pillowy ride. It equals bunching up and saddle sores. So be sure that you've got enough padding, but that it's staying where it should be. Shorts should be tight, yet comfortable. Pull them up past your waist if that's what it takes to get that chamois flat and in place. If you're hurting already, chamois cream isn't a bad idea. I also find that removing any offending hair from the area reduces friction.