Quote Originally Posted by OakLeaf View Post
If you plan to save seeds, then you need to isolate the female flower before it opens, with a little cheesecloth or screen or whatever; and hand pollinate it from the same species of squash with a clean brush.
I just read somewhere that if you get to the flowers first thing in the morning (before even the Mason bees are active), hand pollinate them, and then use a piece of string or yarn to tie the flower shut, you can get pure seeds. I haven't tried it yet, but I plan to eventually!