Sometimes I will inflate my rear more than my front; but this is usually for handling purposes, i.e. on a mountain bike. Don't know why you would do this for a road bike?
I think I remember someone saying to do this because it makes the bumps a bit gentler on the hands. But I don't know the science behind two wheels with different levels of rolling friction.
Fall down six times, get up seven. My Blog/Journal: Fat Athlete