I don't have a long haul trucker and haven't ridden one, so I can't comment.
I do have a surly pacer that's set up with a flat bar and I run 700x28 tires on it... and it feels a bit like a tank. It's still much quicker than my mountain bike on the roads, and I ride it around to commute on. Very comfortable bike. I think I've done my 15 miles on it, and a friend has down about 25 on it.
It's not as quick as my road bikes, but it's still a very nice ride.





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