Mono is caused by the Epstein-Barr virus. It also can cause chronic fatigue syndrome. Two illnesses, one virus.
The CDC explains it better: http://www.cdc.gov/ncidod/diseases/ebv.htm
It is important to note that symptoms related to infectious mononucleosis caused by EBV infection seldom last for more than 4 months. When such an illness lasts more than 6 months, it is frequently called chronic EBV infection. However, valid laboratory evidence for continued active EBV infection is seldom found in these patients. The illness should be investigated further to determine if it meets the criteria for chronic fatigue syndrome, or CFS. This process includes ruling out other causes of chronic illness or fatigue




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