The answer to that depends on what you want most out of the wheels. Aerodynamics, weight, durabilty, price? What kind of bike are you putting them on? What kind of riding do you want them for? What kind of road surfaces? And while I know most people hate to answer this, about how much do you weigh? Sorry; it's relevant when it comes to wheels....

Also, there are lot of factory wheelsets out there by any number of manufacturers. What brands does your shop sell? For what price? What's your budget?