I don't much opinion one way or the other UKE, I just wanted to say congrats of the offer and share an outsiders view of a friends recent choice.
My friend just made the same decision you're facing and he went to work for Big Pharma instead of academia, his decision was based on freedom primarily. In academia he would be forced to spend and inordinate amount of time chasing ever dwindling grant funding to operate the lab he would oversee, as opposed to doing the research he loved. Going corporate offered him the freedom to remain in the lab and out of administration/funding. I don't know if the situation is the same in the UK?



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I think the statement that academic jobs are few and far between is super true in both UK and US. DH is a Brit btw and we have friends on both sides of the pond in both academic and industry/govt jobs. Most of us scientists would relish a non-academic job because of the high stress to publish like a mad fool and make your students happy all to maybe not get tenure after 6 yrs of working your a$$ off. There are so many universities that intentionally hire 2-3 people for each potential tenure track. The results are bloody and horrible. But the freedom academia brings is wonderful, so if you can tough out those 6 yrs, you get to be the snob and can do what you please after that. We have friends struggling in both countries in that pre-stability position and it wreaks havoc on families. And unfortunately, UK funding is way worse than US and both are getting worse by the minute, especially for non-applied (and largely non-human) research. I'd love to be in pure science (biomechanics of gait and stability), but funding would never happen for my ideas unless I can make it work in humans, which isn't always feasible.