I don't much opinion one way or the other UKE, I just wanted to say congrats of the offer and share an outsiders view of a friends recent choice.

My friend just made the same decision you're facing and he went to work for Big Pharma instead of academia, his decision was based on freedom primarily. In academia he would be forced to spend and inordinate amount of time chasing ever dwindling grant funding to operate the lab he would oversee, as opposed to doing the research he loved. Going corporate offered him the freedom to remain in the lab and out of administration/funding. I don't know if the situation is the same in the UK?