I ride a 2005 Isis...but it's a totally different bike because mine is Ti. I believe the geometry is the same though, and I love the bike. LOVE it. Mine is all Ultegra and I've not had any problems at all. I've put more than 5000 miles on it...
I have the Velocity Uriel wheels and I really like them. I'm actually thinking of buying a second pair to put on my other bike. I've never riden a Mavic Ksyrium Elite wheel though, so I can't compare.
Since my Isis is a 19", I have the 650's. I've never had any issue with them. They actually accelerate really well, so I've been pleased. I even had a flat on my MS150 a few years ago and they had a replacement tube available for me at the rest stop. I think that as long as you are talking about 650's and 23mm tires, they are common and easy to find. 650's with wider tires are more unusual and tubes/tires could be harder to locate.



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) on my bike... and oh I wouldn't change them for the world!! You should see me fly going down hill... I love those wheels!!!!!!!!!!!!!!!!
