I had my first saddle sore in May after a long weekend of riding. It was in the crease between by thigh and pubic area and was a large cyst and not an open sore. I used benzoyl peroxide (zit cream, basically) on it. I read that suggestion on another cycling forum I think. It cleared it up within a couple of days. Just be careful, the stuff will bleach your undies, shorts, etc. I tried other things like bag balm, hot baths, neosporin, with no success.