I am very nearsighted and have worn soft contacts for about 30 years. I have cycling sunglasses with 4 shades of lenses. Actually I have 2 pairs; one I keep in my purse for "regular" wear with the darkest lenses. Sometimes I wear them cycling. The other pair, I keep in my bike "cubby" and those have the lighter brown lenses in. I find those fine for most days. I have put the yellow lenses in a couple of times for cloudy/rainy days and if there's any chance of changing conditions, I bring those with me.
I am also pretty farsighted now and wear my reading glasses over my contacts about 50% of the time. I can still see my bike computer, though without them. I stick them in my bike bag, more in case I have to change a flat.
I could never ride with my regular glasses on. They are transition lenses, like Lisa's, but I only wear them when I get into bed. The few times I have had to drive with them freaked me out because I was constantly looking down and I couldn't see through the near vision part! I have never had an issue with contacts during a ride.