I've been on it for years, and I remember the first 6 months being kind of rough (mostly due to moodiness), but it got much better. Lighter, painless periods are a plus, so is clear skin and the ability to anticipate the start of my period within a few hours.

Since I didn't start riding until I'd already been accustomed to it, I can't give info about how it will effect your ride. It often takes some getting used to, but once you adjust, it's definitely got its perks.