I have osteoarthritis and can't take the usual pain relievers because my Crohn's Disease has given me ulcers before. So instead my doc recommended glucosamine (with or without condroitin and/or MSM) and turmeric and ginger. It does seem to be working. I was having knife-like pains. Now I only get vague aches when the weather suddenly turns cold, and warm woolies over plus a workout to build up heat from inside tends to take care of those.