Very interesting - I can't say I have heard of that happening!
I will say though, the ibuprofen is a much safer drug in any event than imitrex - people have cardiac arrests on that stuff!!!
I probably take it 3 or 4 times a week. I could see serious issues with someone taking say 800 mg doses 4 times daily for an extended period of time - I know there are people out there who do that - hence the development of the cox2 inhibitors like vioxx (that and they protect the gut) but that is a whole OTHER discussion.
The best drug is none, but if you have to have something, the one with the lowest risk and side effect profile that is effective and affordable is the best drug for the problem. In this case, Ibuprofen fits that bill.
It is important to tell your doc about ANY drugs you are taking! Yes, even Tylenol (aka Acetaminophen) - that stuff can very deadly if taken too much/too often/in certain illness - it is NOT an innocuous drug. Occasional moderate use is fine - nothing in excess is any good!



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