Wow, I'm so glad I'm not the only one! I've always had some PMS, but lately I've been terrible. I finally gave in and went on an estrogen patch. Felt a lot better, but had yeast infections from hell. I went to a compounding pharmacy and they prescribed two pills: estrogen/testosterone and progesterone. They said that stress kills testosterone in our systems and we end up with crushing fatigue.

Believe me - I am the original flower child and hate to take any kind of meds, but the grumpiness, fuzzy thinking and fatigue were too much. I like to "ride my age" on my birthday and this year I'll be 49, so I have to start to feel better soon!