I have recently (4 mos ago) been able to get myself OFF of migraine medication - imitrex was what I was mostly taking - by taking ibuprofen AHEAD of the attack. If I am going to do something that causes me to have a migraine usually - say stay up late or exercise in the heat - I take 600 mg of ibuprofen. As it turns out If I feel a migraine coming on, I can take a large dose of ibu and I DONT GET A MIGRAINE!!! Now - had ANYbody told me to take ibu for a migraine in the past, I would have laughed them out of the park. It actually works. I have been on imitrex for years -tried topamax, and metoprolol and amyltriptyline and I can't even list all of them. Nothing worked. I got 12 to 15 migraines a month at a minimum. some weeks as many as 5! Imitrex is pretty awful stuff. I havnt had one in over 3.5 mos.

It's easy to think the ibuprofen would be inneffective seeing as it's over the counter - however, migraines are an inflammatory process, and ibuprofen is an effective anti-inflamatory. It's cheap and if you can stomach it, definately worth trying.

I'd love to hear if it works for you. I need a topic for my thesis!