My seat bones were hurting me so much that i could not sit on the bike for a whole week after riding. So I went and had a fitting.
Now good stuff.. they measured my sit bones and also gave me a seat with less padding so my seat bones found there spot and didn't move. I got the specialized ruby gel seat w/ cutout. I'm still a little sore the next day but no sit bone pain. Also I bought the castelli gloves to help with the hand sores.. I have since invested in the Castelli Free bibshorts and LOVE them, nothing wrong with the Izumi's. I have my first charity ride in two weeks. 175 miles in two days.. so far I've only riden 50! Hope this helps!