Hi, I'm the original poster of this thread. Just thought I'd fill everyone in on what finally solved my problem. Even though I had bought top of the line shorts with super padding, the seams were what was causing my discomfort. After several washing and lots of Chamois Butt rubbed into the padding everything softened up and I wasn't irritated anymore. Make no mistake, there were days I thought I'd never get back on my bike because the discomfort was so bad....I was determined and suffered through it anyway. Good luck to all of you that are having the same problem. And many many thanks to all the wonderful advice I received.