I took Inderol many years ago when I first started to get migraines. It made me very emotionless. It also didn't help with the migraines so the doctor took me off it and switched me to a completely different type of drug. So I guess that answers one question - you don't have to take it forever.

I recall that the doctor told me not to expect my heart rate to rise as much during exercise as it did when not on Inderol. However she didn't tell me that I couldn't exercise while taking it.