I'm curious about this too. I've bought and am quite happy with the Jett, but it's a dang hard saddle and if I sit for a long time (3 hrs.+) I get quite bruised and numb. But it's not soft tissue getting squished, just the bones I'm supposed to be sitting on in the first place.

I'm fine on harder faster rides, though, cause I move around more, stand more and pedal harder so there isn't as much steady pressure.