I was born and raised in Cleveland. I moved to the midwest (Indiana, Iowa, Wisconsin) for college and my post-collegiate life. To me, northeast Ohio is definitely not the midwest, nor is it the Ohio River Valley; but I can easily classify other parts of Ohio as such. Many of my midwestern friends, after having been to Cleveland, refuse to categorize it as midwest - they think we're grungy easterners. It's hard to characterize because it touches so many regions - the midwest, Appalachia, the Ohio River Valley, the Great Lakes. I guess Ohioans are kind of like the mutts at the pound - no one really knows how to describe us, but we sure are loveable.
"The north is too cold,
the west too barren,
the south too hot, and
the east too bloody.
Iowa is just right."
- Old Meskwaki saying