Off the top of my head, and people with better knowledge of bike engineering can chime in:

Bottom bracket may be lower, reducing your ground clearance in cornering (and in crossing obstacles on a MTB)

A shallower head angle, resulting in greater trail and slower steering

A steeper seat angle, meaning saddle has to be set farther back to maintain your desired KOPS, potentially reducing your choice of seatposts; also potentially causing your butt to run into your seat when you stand to climb.

Again these aren't necessarily problems, but Amy didn't say what kind of problems she was having, and these may have been among them.