Backpacks, I found, put my center of gravity too high and make me feel unstable. I didn't care for a messenger bag, as it stuck me in bad places. Ouch. I did have a lot of luck with the REI Singular bag...a single strap, teardrop shaped backpack that sat low on my back, and didn't hurt. But then, I got rear-ended in my truck, ended up with a herniated disc in my neck, and now can't/don't ride with anything on my back (other than a Camelback when mountainbiking), and go with panniers. My panniers do stick out of the sides by a bit, but I don't worry about aero with them. Yeah, strong crosswinds are an adventure...
2007 Seven ID8 - Bontrager InForm
2003 Klein Palomino - Terry Firefly (?)
2010 Seven Cafe Racer - Bontrager InForm
2008 Cervelo P2C - Adamo Prologue Saddle