I've taken a Womantours trip that was wonderful. It was a short one (4 days on the DelMarVa peninsula, which I stretched out to 5 by doing a day on my own), but they take such great care of you, and they find some interesting routes to ride and unique places to stay.

Slowbutsteady, the "Okefenokee Challenge" sounds like a great idea too. One of my best friends is turning 50 later this year and she wants to kayak the Okefenokee. Maybe I can talk her/train her into doing the cycling part also.