Welcome guest, is this your first visit? Click the "Create Account" button now to join.

To disable ads, please log-in.

Shop at TeamEstrogen.com for women's cycling apparel.

Results 1 to 15 of 40

Threaded View

  1. #20
    Join Date
    Oct 2007
    Location
    MD
    Posts
    1,626
    It should be said that many many many (add lots more manys) drugs are used off label. That in and of itself isn't so alarming. here is the link to some info about the FDA warning. If it were me, I would just be sure to take this with me and ask the people involved what they think about it. I'm sure they know about it and I'm sure they can adequately address it for you at the time and put your mind at ease.

    http://www.medscape.com/viewarticle/568498

    EDIT - ok, looks like that may not work as you may have to have a membership that I have due to work. how about this
    http://www.fda.gov/medwatch/safety/2...eupogen_PI.pdf

    and here was the paragraph leading up to the revision in the label.

    FDA Warns Against Off-Label Use of Filgrastim Injection (Neupogen)

    On September 5, 2007, the FDA approved safety labeling revisions for filgrastim injection (Neupogen; Amgen, Inc) to warn against its use for peripheral blood progenitor cell mobilization in healthy donors.

    Use of filgrastim for this unapproved indication has resulted in alveolar hemorrhage manifesting as pulmonary infiltrates and hemoptysis requiring hospitalization, the FDA said, noting that hemoptysis resolved with discontinuation of therapy.

    Filgrastim is a granulocyte colony-stimulating factor indicated for use in patients with cancer receiving myelosuppressive chemotherapy or bone marrow transplant, patients with acute myeloid leukemia receiving induction or consolidation chemotherapy, patients with cancer undergoing peripheral blood progenitor cell collection and therapy, and patients with severe chronic neutropenia.


    Again, that may sound worse than it is and I am not for a second saying don't do this. Just that were this me, this is something I would talk to the Drs about first and get all the information that I can. They will know much more than I can find out by searching online. Naturally.
    Last edited by Possegal; 03-05-2008 at 11:42 AM.

 

 

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •