Sidi Dominator Mega works for me and my orthotics. My size is a woman's size 11, medium width, and I have high volume feet. Most women in the US that wear 11 + wear men's gear most of the time. Thankfully I have a job where I am supposed to wear workboots, so shopping isn't a hassle as men's size 10 boots are easy to find.

If you are thinking orthotics, get them first. Or your shoes may not fit your feet with your orthotics in the shoe. After I got mine I had to give away $100s of dollars worth of shoes and boots, which kinda sucked.

So, I bought a men's size 44 for my bike shoes. I find with orthotics I usually have to go up a half size either in length or width, that's a men's 10.5 for you keeping track at home. SIDI of course doesn't make a women's size 44.

In SIDI land, mega refers to their "wide" width. Dominator has a rugged sole, which they call a mountain bike sole. I much prefer MTB shoes because I have speedplay frogs, and the cleats for the speedplays aren't recessed, so the rugged sole works better. When I ride my MTB I wear boots.

The fit is OK, heel is a bit sloppy and wouldn't work for running, but they are perfect for biking. My only gripe is the top strap is a skosh too short, so it is really hard to start it.