If you don't need it don't use it!
I have never ever needed it except for a long bike trip we were on for a week. No showers! When we finally reached a lake we could all wash off at, i washed the shorts i was wearing and put on a pair of dry clean one's. For some reason these shorts started to rub in a bad area. I had to use something. I had a tube of monistat chafing relief powder gel and it was great. But that is the only time I have had to use something. Oh and my shorts were not the most expensive so that could be another reason. Don't buy cheap shorts. Lessoned learned on my part!