Are you using a night splint? Fortunately I only get mild CTS, but sleeping in a splint for a few days is usually all it takes.

Also, clicking a mouse button puts a lot of stress on my wrist nerves. I'm much happier since I set up my touch pad for tap-click.

+1 on the B6 and Omega-3s.

And BTW, nerve damage is *not* irreversible. Nerves take a long, long time to heal, but with the exception of some parts of the spinal cord, they *do* heal. I've bruised nerves twice, and cut a minor sensory nerve, with full recovery in all cases.