I had a long response typed out last night and lost it!
Yes, I ride fixie! My boyfriend/coach who just did Furnace Creek 508 (yes...it's a 508 mile race!) on his FG (49/16) got me hooked recently. I'm currently riding his Pinarello Pista, but we're going to build a Milwaukee steel frame fixie for me eventually. My gearing is 46/17 right now.
Check out his website www.epictrain.com for lots of good info. He has a gear inch calculator there, here's the direct link to it... http://epictrain.com/files/Gear_Inch_Calculator.xls Play around with it and input your current gearing and the gearing that you're thinking of using (50/16) to see the variance in cadence at certain speeds.



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