Another happy Ruby rider here. 5-1 with a 27.5 inseam.

I ride a 44cm S-Works. I used to ride a 48cm, but it was too big. Sure, I could ride it somewhat comfortably but performance-wise, I needed a smaller, stiffer frame. Personally, I would NOT get a road bike with 650 wheels (TT bike is a different story), but it has a lot to do with the accessibility of different wheelsets.

I have shorter legs, but have not found the steeper angles to be any less comfortable or responsive, whether sprinting or on hillier centuries. In fact, I have experienced no downside at all to this bike's geometry.