Last year, I started having vv leg pain at night, very sharp and sleep-ruining. My holistic doc put me on 2 supplements - 1 called Varicosin, that has the classic natural remedies for varicose veins - horse chesnut, ginko, etc, and Nattokinase, which is a soy derivative to help rebuild/build new capillaries. After about six months of taking them, I'm tailing off without any pain returning as of yet. Also, for short term treatment I found that the Tiger Balm muscle rub helped a lot. When the pain was bothering me nightly, I just got in the habit of applying it at the site before I got into my pajamas. Good luck with this, I'm sure with a little experimenting you'll find the remedy.