I ride with 1/2 strength cranberry juice + electrolytes. I drain out everything I can, rinse out the reservoir and then drain it through the tube until it runs clear. Then, I add one drop of dishwasher liquid, shake it up, and drain it through the tube. Then I rinse the reservoir clear of soap and then drain, again, through the tube. Then, I do a preliminary drying inside with a paper towel, then stuff it with a clean, dry paper towel and hang it to dry. Every so often I'll clean out the tube with a special tube brush. It sounds like a lot of work, but it really only takes a few minutes. Of course, I'm sometimes so tired from my ride that I need to leave it til later in the day.