Another righty who unclips left. But, like others, my left side is much stronger, so it's not the starting out with the stronger leg thing. I pretty much do everything lefty, except writing. My laterality is really messed up, along with my depth perception, so I do what won't kill me. No one ever told me which side to clip in/out of. I think that originally started doing the right side, but for some reason I switched. I think I would kill myself if I tried to unclip on the right on my road bike, but on my mountain bike, sometimes I do. I can barely take my right hand off the bar to signal that's how weird I am, never had any problems with the left. I can only do the water bottle with my left hand, too (hey, at least I can drink and ride now, without the Camelbak).