Sometimes seat trouble comes from the way you are sitting on the saddle. On a road bike you are not supposed to just sit straight up and bend over to the handle bar. You should pick yourself up on your pedals and rotate your hips slightly (sticking your butt up in the air). I am much more comfortable with my sit bones on the very back of the saddle. Plus it takes a while to build up a sort of callus that comes with time in the saddle. Not that there really is a callus per say, it is like breaking in a new pair of shoes, every spring you also have to break in your butt/crotch when you get a new bike or after a few months or weeks off. With the right saddle and position it gets better quickly.

PS- it sounds like you have the nose too high. Take a yard stick and place it long ways on the saddle to see if it is level. Or it could be your bike is too big for you. Ask some seasoned cyclists or racers if possible.