This has been said many times before, but test ride as many different bikes as you can.

My first road bike was a used Trek 2200. Nice bike and I loved it, but wanted to upgrade to carbon. I really wanted another Trek (I have a thing about supporting US companies) but when I went for my fitting/measuring at my LBS, I was told the LeMond series bike would be a better fit.

I bought a beautiful LeMond Versailles. I love it and have no comfort issues.

Last advice: get fit/measured. Ask what bike would be a good fit for your body.

You might not get exactly what you wanted, but you will be happy!