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  1. #1
    Join Date
    Sep 2004
    Location
    Charlotte, NC
    Posts
    508

    Reference RE: Vit C

    I found this information in the NY times. Here is the article:

    NATIONAL DESK | June 15, 2001, Friday

    Vitamin C Pills Tied to DNA Risk

    ( AP ) 367 words
    Late Edition - Final , Section A , Page 26 , Column 1

    ABSTRACT - University of Pennsylvania study led by Ian C Blair finds that vitamin C pills that millions of health-conscious Americans take may actually help produce poisons that can damage DNA, a step toward forming cancer cells; findings do not mean that vitamin C causes cancer, but does sound warning about use of vitamin C pills; study is published in journal Science (S)

    I did not read the original article.

    Here is the original article:

    Science 2001 Jun 15;292(5524):2083-6 (ISSN: 0036-8075)
    Lee SH; Oe T; Blair IA
    Center for Cancer Pharmacology, University of Pennsylvania, 1254 BRB II/III, 421 Curie Boulevard, Philadelphia, PA 19104-6160, USA.

  2. #2
    Join Date
    Jul 2003
    Location
    La Crescenta, CA
    Posts
    39

    Thankyou,

    I check into that , thanks for the info.
    donna

  3. #3
    Join Date
    Jul 2003
    Location
    Traveling Nomad
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    6,763
    Hi Autumnbreez,

    I like TwinLab Daily One Caps (Multi-vit/mineral supplement WITHOUT iron). It's allergen free and has extra Folic Acid (good for the heart). Available at Vitamin World and probably many other places.

    I like and use daily: Vitamin World's house brand of protein powder in vanilla flavor. Yummy!

    Emily
    Emily

    2011 Jamis Dakar XC "Toto" - Selle Italia Ldy Gel Flow
    2007 Trek Pilot 5.0 WSD "Gloria" - Selle Italia Diva Gel Flow
    2004 Bike Friday Petite Pocket Crusoe - Selle Italia Diva Gel Flow

  4. #4
    Join Date
    Sep 2004
    Location
    Charlotte, NC
    Posts
    508
    Quote Originally Posted by emily_in_nc
    Hi Autumnbreez,

    I like TwinLab Daily One Caps (Multi-vit/mineral supplement WITHOUT iron). It's allergen free and has extra Folic Acid (good for the heart). Available at Vitamin World and probably many other places.

    I like and use daily: Vitamin World's house brand of protein powder in vanilla flavor. Yummy!

    Emily
    Why the huge emphasis on "without iron"? Most women do not get enough iron in their diet. It's especially difficult for vegetarians. Except for the rare person with hemochromatosis, the body can handle small excesses of iron just fine. Anemia is a very common problem in the USA despite our abundance of food.

  5. #5
    Join Date
    Jul 2003
    Location
    Traveling Nomad
    Posts
    6,763
    Quote Originally Posted by doc
    Why the huge emphasis on "without iron"? Most women do not get enough iron in their diet. It's especially difficult for vegetarians. Except for the rare person with hemochromatosis, the body can handle small excesses of iron just fine. Anemia is a very common problem in the USA despite our abundance of food.
    Iron supplements kill my stomach/intestines. I just can't take them. I am not even close to anemic, according to my hematocrit levels, which my doc checks regularly. I get plenty of iron in my diet (or am good at holding onto what I do have, even though I do menstruate), so have no need to take extra and mess up my tummy. That's all. It can be quite hard to find a multi-vit/min tablet without iron, which is why I put the emphasis there. I looked fairly long to find this one and have been very satisfied with it.

    Emily
    Emily

    2011 Jamis Dakar XC "Toto" - Selle Italia Ldy Gel Flow
    2007 Trek Pilot 5.0 WSD "Gloria" - Selle Italia Diva Gel Flow
    2004 Bike Friday Petite Pocket Crusoe - Selle Italia Diva Gel Flow

  6. #6
    Join Date
    May 2004
    Location
    Longmont, CO
    Posts
    545
    Quote Originally Posted by emily_in_nc
    Iron supplements kill my stomach/intestines. I just can't take them. I am not even close to anemic, according to my hematocrit levels, which my doc checks regularly. I get plenty of iron in my diet (or am good at holding onto what I do have, even though I do menstruate), so have no need to take extra and mess up my tummy. That's all. It can be quite hard to find a multi-vit/min tablet without iron, which is why I put the emphasis there. I looked fairly long to find this one and have been very satisfied with it.

    Emily
    I don't really "get" the whole menstruation/iron problem. I mean, yes, we lose some blood, but it doesn't seem like it's that *much* blood, does it? I think I've lost more blood on some rides than I ever have during my period! Then again, I've always been blessed with light ones.

    I get that blood contains iron, but do we really lose enough blood for it to be significant? Or is there some other factor I'm missing?
    monique

  7. #7
    Join Date
    Mar 2005
    Posts
    165
    Quote Originally Posted by bounceswoosh
    I don't really "get" the whole menstruation/iron problem. I mean, yes, we lose some blood, but it doesn't seem like it's that *much* blood, does it? I think I've lost more blood on some rides than I ever have during my period! Then again, I've always been blessed with light ones.

    I get that blood contains iron, but do we really lose enough blood for it to be significant? Or is there some other factor I'm missing?
    The idea is, that there are very few ways to get rid of iron. The main way is bleeding, including menstruation. Yeah, you only lose a few ounces of fluid per period, and only part of that is actual blood, but if you didn't menstruate, the iron you consumed would stay with you for a long time. I think heavy sweating also sheds some heavy metal.

    So if you're a menstruator OR an endurance athlete, you need to replenish your iron fairly regularly. (If not, iron can build up and as a potent oxidizer it has been thought to contribute to some disease states, so for example sedentary non-menstruators shouldn't probably take it supplementally.) It takes some thinking to make sure to get it from diet (leafy greens, lentils, molasses, cooking in iron pots, fortified foods, red meats) so if you DO have ways to get rid of it (bleeding and sweating) then it shouldn't do any harm to take it in supplement form. But it can cause constipation so watch out for that!

  8. #8
    Join Date
    Mar 2005
    Posts
    165
    Quote Originally Posted by doc
    Science 2001 Jun 15;292(5524):2083-6 (ISSN: 0036-8075)
    Lee SH; Oe T; Blair IA
    Center for Cancer Pharmacology, University of Pennsylvania, 1254 BRB II/III, 421 Curie Boulevard, Philadelphia, PA 19104-6160, USA.
    As far as I can tell, this study compares the damage caused by vitamin C in the *absence* of transition metals (like Iron) to the damage done *by* such metals. The conclusion? They're quite similar, and C might be a smidge more effective at promoting the reaction that results in the potential damage. But the thing of it is, C is so good at scavenging reactive oxygen, that it's pretty much used up by the copious free radicals in the body, which is why the transition metals had to be chelated off for the experiment to work. (The presence of transition metal ions in vit C solutions causes a relatively rapid loss in absorbance at 265 nm resulting from oxidation of vit C to its dehydro form. CuII is approximately 80 times more effective than FeIII at oxidizing vit C (20).)

    The conclusion was that more studies need to be done, that maybe this is why C isn't therapeutic against cancer, and that people who are at risk for "lipid hydroperoxide-mediated DNA damage" might want to keep tabs on their vitamin C ingestion.

    'Least that's how I read it.

 

 

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