I've had mixed sucess with tire liners. I had them in my old bike and I went about 15 years flat free - yes that's 15 years, with 700c tires. I put some in my winter bike this year and I got 3 flats in 2 days, 2 of them caused by the liner itself (one from the trainer rubbing over the overlap...). That was with 650's - I think that the liners just did not agree with those tires/wheels. I definitely like original Mr. Tuffys over slime liners - much easier to install properly.
I've never personally used tire sealants - though I bought a used disc wheel that already had it and it sure does work - but I don't know what brand - def. not slime since it was not green. That tire will leak slowly, but it will hold 150 psi for an hour or better, which is pretty good.
We also bought some slime for a friend of ours who uses a wheelchair and seemed to have perennial flats. He really loves it - he's not always pumping up his tires or listing to one side. Wheelchair tires generally are much lower pressure than bike tires though.



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I had to do my back wheel yesterday (pump got stuck on the valve and DH pulled the valve out of the tube getting the pump off
). But i insisted on changing it myself cos i know one day i'll have to do that on the road. Took me 45 minutes

