I've had a number of them over the years, the most recent in my right knee. I have very little cartilidge left and I couldn't walk very far. The shot took more than a week to kick in which was longer than they have taken in the past. I am now several months past the shot and it's still keeping the inflammation pretty well at bay. My left knee is titanium, so no more shots in that one!



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I felt like the range of motion was instant, but it was probably the next day....
