Hey Kano - I know what you mean about that issue of impact in the thumb web area. Sometimes I need to relax my hold on the hoods and sometimes its just a very long ride and I don't have enough meat on my hands to bear all that pounding. I also picked up a pair of 2007 specialized bg gel glove because they are one of the few gloves that have padding that wraps around the base of the thumb and around the base of the pointer finger. So far that and remembering not to grip my hoods too much has resolved my issue. Happy hands for me!