I haven't tried SealSkinz, but I do have a pair of GoreTex socks with work great. I've worn them running through bogs with water up to my ankles and my feet stayed dry. Didn't quite work last week when I cycled home after torrential rain, but that had more to do with the water beeing knee deep where the path had flooded. As long as the water doesn't run in over the top, they keep you dry.