I was having the same problems, suddenly, after riding for 5 plus years with the same cut out saddle. Got my new bike and ouch!! Although I did not not have any cysts, I was raw and red on my left side, in the areas you described. I bought a Terry Firefly racing saddle and it improved a bit, but then tried a Brooks for 4-5 months. The Brooks saddle was torture for me. I broke it in, but the issue never went away. In my case, it was menopausal stuff causing the problem. The slight change in the geometry of my new bike set it all off. My doctor prescribed a Estring, which provides a continual low dose of estrogen to the vaginal area only. This way, it doesn't get "washed out" like the cream, or get into your bloodstream. This also has been a big help to, ah, other "areas" of my life. I switched back to the Firefly saddle and now all is perfect.