When you loosen the QR, hold the nut still and only turn the lever side. (and count how many whole turns you do) If you turn the nut, too, it changes where the wheel sits when you put the wheel back on.
If it looks wonky when you get the QR tightened, loosen it again and adjust the side that is off (nut or lever)
If it looks like the brakes go wonky (not the wheel) squeeze the brakes a couple times or play with the arms (depending on your brake) to recenter the pads.
"If Americans want to live the American Dream, they should go to Denmark." - Richard Wilkinson