I take Celebrex for arthritis in my hands, following years of horseshoeing. My hands would be curled into little balls, somewhat like the arthritis sufferer in Staphen King's "Precious Things." I have recently been debating asking if I can get a higher dosage, since I seem to be rubbing my hands like in the old days before Celebrex. BTW, if you take a double dosage, it will make the most horrendous period cramps disappear. For days.