Lol - it looks like a good idea if you live in a high theft area (NYC, any college campus…). Around here you don't see so many bike parts go missing so much as entire bikes, unless the bike has been sitting out in public for a while - then parts seem to start going missing little by little.

I'd personally never replace my quick releases. I'm taking wheels on and off way too much to want to have to crank them on and off with an actual bolt, but if the price is right I can see them being popular in places that you can't leave an unlocked wheel or a QR seat post for 5 min without it walking off. Bike thieves are quite sophisticated these days and carry enough tools that I can imagine that even a regular bolt is no contest if they want your wheels.