While I don't doubt the benefit of healthy diet and exercise to reverse CAD, or metabolic syndrome, I think it's a bit of pseudo science to attribute this all to "juicing."
Some people need to take "all those medicines" despite extensive endurance exercise, healthy eating, and lifestyle. To say you are going to get off of them, is an admirable goal, but I hope your brother has had an extensive physical with a good cardiologist, that includes a stress test. Preferably, one with dye that would show any blockages that are a result of his unhealthy lifestyle. If he's that much of a couch potato, he might be a walking time bomb, with no symptoms.