Our older female dog, in my avatar, developed this problem over the past year. We too tried a drug that worked great; unfortunately, our pup has a sensitive liver (nearly died from liver failure about 5 years ago) and the drug was elevating her bad liver levels so we had to take her off. We got very tired of having to clean her dog beds constantly. We now use doggy diapers at night - a disposable one on the inside that we get at Pet Smart, covered by this washable one (we have 2 so one is always clean and ready to go): http://www.carealotpets.com/Products...rs__2603e.aspx. We found that the washable one worked fine on its own when she just dribble leaks, but for nights when she has a full bladder emptying, the inside diaper is a necessity so now we just go with both. She's happier and we are happier.